Modification of Multiliposomal Nanocontainers with Albumin as a Method for Increasing Their Resistance to Enzymatic Hydrolysis
نویسندگان
چکیده
The influence of a pancreatic enzyme, lipase, on doxorubicin-loaded anionic liposomes, their complexes with spherical polycationic brushes, and ternary brushes bovine serum albumin has been studied. two-stage kinetics the enzyme-induced disturbance liposomal membrane integrity investigated using fluorescence spectroscopy. A 120-min induction period free any serious damage to liposome membranes found for all enzyme-treated samples. This is followed by rapid release encapsulated doxorubicin. Enzymatic hydrolysis liposomes binary proceed at same rate, while rather long resistance observed complexes. It assumed that plays role sterically screening agent, which hinders enzymatic in multiliposomal
منابع مشابه
a comparison of teachers and supervisors, with respect to teacher efficacy and reflection
supervisors play an undeniable role in training teachers, before starting their professional experience by preparing them, at the initial years of their teaching by checking their work within the proper framework, and later on during their teaching by assessing their progress. but surprisingly, exploring their attributes, professional demands, and qualifications has remained a neglected theme i...
15 صفحه اولenzymatic pre-hydrolysis of high fat content dairy wastewater as a pretreatment for anaerobic digestion
enzymatic extract preparation from pseudomonas aeruginosa km110 under accession no. hq730879 with lipase activity (0.3 u/ml), was used to perform enzymatic hydrolysis pretreatment of a synthetic dairy wastewater with 1000 mg/l total fat content. the pretreatment was optimized for 48 h hydrolysis time, at 45æ% c with 10% v/v enzymatic extract. the biological treatment of synthetic dairy wastewa...
متن کاملenzymatic pre-hydrolysis of high fat content dairy wastewater as a pretreatment for anaerobic digestion
enzymatic extract preparation from pseudomonas aeruginosa km110 under accession no. hq730879 with lipase activity (0.3 u/ml), was used to perform enzymatic hydrolysis pretreatment of a synthetic dairy wastewater with 1000 mg/l total fat content. the pretreatment was optimized for 48 h hydrolysis time, at 45æ% c with 10% v/v enzymatic extract. the biological treatment of synthetic dairy wastewat...
متن کاملMaterials and method for increasing a plant's resistance to stress
Method of increasing resistance to a pathogen or a pest in a plant comprising introducing into the plant and expressing therein a polynucleotide comprising a nucleotide sequence encoding a Qua-Quine Starch (QQS) polypeptide; method of producing a plant with increased resistance to a pathogen or a pest comprising crossing a plant obtained in accordance with the above method with a second plant t...
متن کاملEnzymatic Hydrolysis as an Environmentally Friendly Process Compared to Thermal Hydrolysis for Instant Coffee Production
Conventional production of instant coffee is based on solubilisation of polysaccharides present in roasted coffee. Higher process temperatures increase the solubilisation yield, but also lead to carbohydrate degradation and formation of undesirable volatile compounds. Enzymatic hydrolysis of roasted coffee is an alternative to minimize carbohydrate degradation. In this work, products obtained f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Colloid journal of the Russian Academy of Sciences
سال: 2021
ISSN: ['1061-933X', '1563-1702', '1608-3067']
DOI: https://doi.org/10.1134/s1061933x21020113